Identification of the Fosl1/AMPK/autophagy axis involved in apoptotic and inflammatory effects following spinal cord injury.
Sign Up to like & getrecommendations! Published in 2021 at "International immunopharmacology"
DOI: 10.1016/j.intimp.2021.108492
Abstract: Strategies for reducing spinal cord injury (SCI) have become a research focus because an effective treatment of SCI is unavailable. The objective of this study was to explore the underlying mechanisms of Fosl1 following SCI.… read more here.
Keywords: fosl1; apoptosis; cord injury; ampk ... See more keywords
FOSL1 promotes tumorigenesis in colorectal carcinoma by mediating the FBXL2/Wnt/β-catenin axis via Smurf1.
Sign Up to like & getrecommendations! Published in 2021 at "Pharmacological research"
DOI: 10.1016/j.phrs.2020.105405
Abstract: Colorectal carcinoma (CC), one of the most prevalent digestive cancers with high mortality and morbidity globally, still lacks powerful therapies to improve the prognosis. Here, we established that the expression of fos-like antigen-1 (Fosl1) was… read more here.
Keywords: fosl1; smurf1; wnt catenin; colorectal carcinoma ... See more keywords
Hsa_Circ_0005044 Promotes Osteo/Odontogenic Differentiation of Dental Pulp Stem Cell Via Modulating miR-296-3p/FOSL1.
Sign Up to like & getrecommendations! Published in 2022 at "DNA and cell biology"
DOI: 10.1089/dna.2022.0394
Abstract: Circular RNAs (circRNAs) are a form of RNAs that lack coding potential. The role of such circRNAs in dental pulp stem cell (DPSC) osteo/odontogenic differentiation remains to be determined. In this study, circRNA expression profiles… read more here.
Keywords: fosl1; mir 296; circ 0005044; differentiation ... See more keywords
FOSL1 Inhibits Type I Interferon Responses to Malaria and Viral Infections by Blocking TBK1 and TRAF3/TRIF Interactions
Sign Up to like & getrecommendations! Published in 2017 at "mBio"
DOI: 10.1128/mbio.02161-16
Abstract: ABSTRACT Innate immune response plays a critical role in controlling invading pathogens, but such an immune response must be tightly regulated. Insufficient or overactivated immune responses may lead to harmful or even fatal consequences. To… read more here.
Keywords: traf3 trif; malaria viral; ifn; viral infections ... See more keywords
FOSL1 Promotes Kras‐induced Lung Cancer through Amphiregulin and Cell Survival Gene Regulation
Sign Up to like & getrecommendations! Published in 2018 at "American Journal of Respiratory Cell and Molecular Biology"
DOI: 10.1165/rcmb.2017-0164oc
Abstract: &NA; The FOSL1/AP‐1 transcription factor regulates gene expression, thereby controlling various pathophysiological processes. It is a major effector of RAS‐ERK1/2 signaling and is activated in human lung epithelia by tumorigenic stimuli. Recent evidence shows an… read more here.
Keywords: kras induced; lung cancer; fosl1; gene ... See more keywords
Misexpression of LINC01410, FOSL1, and MAFB in peripheral blood mononuclear cells associated with diabetic nephropathy.
Sign Up to like & getrecommendations! Published in 2023 at "Gene"
DOI: 10.2139/ssrn.4218409
Abstract: AIMS Currently, diabetic nephropathy (DN) is considered the leading cause of the end-stage renal disease (ESRD). However, its specific molecular mechanism is still unclear, and there is still a lack of effective diagnostic and therapeutic… read more here.
Keywords: fosl1; linc01410 fosl1; mafb fosl1; fosl1 mafb ... See more keywords
FOSL1 promotes tumor growth and invasion in ameloblastoma
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.900108
Abstract: Background FOSL1, a key component of the Activating protein-1 (AP-1) transcriptional complex, plays an important role in cancer cell migration, invasion, and proliferation. However, the impact of FOSL1 in ameloblastoma (AM) has not been clarified.… read more here.
Keywords: fosl1; promotes tumor; growth; expression ... See more keywords
FosL1 Is a Novel Target of Levetiracetam for Suppressing the Microglial Inflammatory Reaction
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms222010962
Abstract: We previously showed that the antiepileptic drug levetiracetam (LEV) inhibits microglial activation, but the mechanism remains unclear. The purpose of this study was to identify the target of LEV in microglial activity suppression. The mouse… read more here.
Keywords: levetiracetam; target; expression; lev ... See more keywords