Articles with "founder strains" as a keyword



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A comprehensive and comparative phenotypic analysis of the collaborative founder strains identifies new and known phenotypes

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Published in 2020 at "Mammalian Genome"

DOI: 10.1007/s00335-020-09827-3

Abstract: The collaborative cross (CC) is a large panel of mouse-inbred lines derived from eight founder strains (NOD/ShiLtJ, NZO/HILtJ, A/J, C57BL/6J, 129S1/SvImJ, CAST/EiJ, PWK/PhJ, and WSB/EiJ). Here, we performed a comprehensive and comparative phenotyping screening to… read more here.

Keywords: founder; phenotypic analysis; comparative phenotypic; comprehensive comparative ... See more keywords
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High-throughput sleep phenotyping produces robust and heritable traits in Diversity Outbred mice and their founder strains.

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Published in 2020 at "Sleep"

DOI: 10.1093/sleep/zsz278

Abstract: STUDY OBJECTIVES This study describes high-throughput phenotyping strategies for sleep and circadian behavior in mice, including examinations of robustness, reliability, and heritability among Diversity Outbred (DO) mice and their eight founder strains. METHODS We performed… read more here.

Keywords: founder; diversity outbred; founder strains; outbred mice ... See more keywords
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Brain gene expression differences related to ethanol preference in the collaborative cross founder strains

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Published in 2022 at "Frontiers in Behavioral Neuroscience"

DOI: 10.3389/fnbeh.2022.992727

Abstract: The collaborative cross (CC) founder strains include five classical inbred laboratory strains [129S1/SvlmJ (S129), A/J (AJ), C57BL/6J (B6), NOD/ShiLtJ (NOD), and NZO/HILtJ (NZO)] and three wild-derived strains [CAST/EiJ (CAST), PWK/PhJ (PWK), and WSB/EiJ (WSB)]. These… read more here.

Keywords: brain; preference; expression; ethanol preference ... See more keywords