Confirmation of the Disulfide Connectivity and Strategies for Chemical Synthesis of the Four-Disulfide-Bond-Stabilized Aspergillus giganteus Antifungal Protein, AFP
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Natural Products"
DOI: 10.1021/acs.jnatprod.2c00954
Abstract: Emerging fungal infections require new, more efficient antifungal agents and therapies. AFP, a protein from Aspergillus giganteus with four disulfide bonds, is a promising candidate because it selectively inhibits the growth of filamentous fungi. In… read more here.
Keywords: disulfide; aspergillus giganteus; four disulfide; synthesis ... See more keywords
A role for whey acidic protein four-disulfide-core 12 (WFDC12) in the pathogenesis and development of psoriasis disease
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.873720
Abstract: Whey acidic protein four-disulfide core domain protein 12 (WFDC12) has been implicated in the pathogenesis of psoriasis but the specific molecular mechanism is not clearly defined. In this study, we found the expression of WFDC12… read more here.
Keywords: wfdc12; protein four; four disulfide; whey acidic ... See more keywords