The four-helix bundle in cholinesterase dimers: Structural and energetic determinants of stability.
Sign Up to like & getrecommendations! Published in 2019 at "Chemico-biological interactions"
DOI: 10.1016/j.cbi.2019.06.012
Abstract: The crystal structures of truncated forms of cholinesterases provide good models for assessing the role of non-covalent interactions in dimer assembly in the absence of cross-linking disulfide bonds. These structures identify the four-helix bundle that… read more here.
Keywords: four helix; structural energetic; dimerization; helix bundle ... See more keywords
Spatial attributes of the four-helix bundle group of bacteriocins - The high-resolution structure of BacSp222 in solution.
Sign Up to like & getrecommendations! Published in 2018 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2017.10.158
Abstract: BacSp222 is a multifunctional bacteriocin produced by Staphylococcus pseudintermedius strain 222, an opportunistic pathogen of domestic animals. At micromolar concentrations, BacSp222 kills Gram-positive bacteria and is cytotoxic toward mammalian cells, while at nanomolar doses, it… read more here.
Keywords: four helix; structure bacsp222; helix bundle; structure ... See more keywords
Important Structural Features of Thiolate-Rich Four-Helix Bundles for Cu(I) Uptake and Removal
Sign Up to like & getrecommendations! Published in 2023 at "Inorganic Chemistry"
DOI: 10.1021/acs.inorgchem.2c04490
Abstract: A family of bacterial copper storage proteins (the Csps) possess thiolate-lined four-helix bundles whose cores can be filled with Cu(I) ions. The majority of Csps are cytosolic (Csp3s), and in vitro studies carried out to… read more here.
Keywords: helix bundles; four helix; classical csp3s; uptake removal ... See more keywords