Molecular Origin of the Stability Difference in Four Shark IgNAR Constant Domains.
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DOI: 10.1016/j.bpj.2019.04.013
Abstract: Improving the stability of antibodies for manufacture and shelf life is one of the main focuses of antibody engineering. One stabilization strategy is to perform specific mutations in human antibodies based on highly stable antibodies… read more here.
Keywords: molecular origin; constant domains; four shark; stability ... See more keywords