Interactions of TonB-dependent transporter FoxA with siderophores and antibiotics that affect binding, uptake, and signal transduction.
Sign Up to like & getrecommendations! Published in 2023 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2221253120
Abstract: The outer membrane of gram-negative bacteria prevents many antibiotics from reaching intracellular targets. However, some antimicrobials can take advantage of iron import transporters to cross this barrier. We showed previously that the thiopeptide antibiotic thiocillin… read more here.
Keywords: bisucaberin; foxa; transporter foxa; signal transduction ... See more keywords
FoxR is an AraC‐like transcriptional regulator of ferrioxamine uptake in Salmonella enterica
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DOI: 10.1111/mmi.14970
Abstract: Salmonella enterica spp. produce siderophores to bind iron with high affinity and can also use three xenosiderophores secreted by other microorganisms, ferrichrome, coprogen, and ferrioxamine. Here we focused on FoxA, a TonB‐dependent transporter of ferrioxamines.… read more here.
Keywords: foxr; foxa; salmonella; regulator ... See more keywords
Synergistic co-regulation and competition by a SOX9-GLI-FOXA phasic transcriptional network coordinate chondrocyte differentiation transitions
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DOI: 10.1371/journal.pgen.1007346
Abstract: The growth plate mediates bone growth where SOX9 and GLI factors control chondrocyte proliferation, differentiation and entry into hypertrophy. FOXA factors regulate hypertrophic chondrocyte maturation. How these factors integrate into a Gene Regulatory Network (GRN)… read more here.
Keywords: foxa; sox9; differentiation transitions; sox9 gli ... See more keywords