The clinical and sleep manifestations in children with FOXG1 syndrome
Sign Up to like & getrecommendations! Published in 2023 at "Autism Research"
DOI: 10.1002/aur.2916
Abstract: FOXG1 syndrome is a rare neurodevelopmental disorder associated with severe cognitive dysfunction, autistic behavior, and early‐onset hyperkinetic movement disorders. Patients have also been reported to experience sleep disturbances. However, these findings are mainly based on… read more here.
Keywords: foxg1 syndrome; manifestations children; sleep manifestations; clinical sleep ... See more keywords
Multimodal epigenetic changes and altered NEUROD1 chromatin binding in the mouse hippocampus underlie FOXG1 syndrome
Sign Up to like & getrecommendations! Published in 2023 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2122467120
Abstract: Significance Mutations in the FOXG1 gene cause a rare neurodevelopmental disorder called “FOXG1-syndrome”. FOXG1 is a key instructor of the developing telencephalon, and patients present with various phenotypes including microcephaly, seizures, and cognitive dysfunctions. We… read more here.
Keywords: multimodal epigenetic; foxg1 syndrome; mouse; syndrome ... See more keywords
Loss of Foxg1 Impairs the Development of Cortical SST-Interneurons Leading to Abnormal Emotional and Social Behaviors.
Sign Up to like & getrecommendations! Published in 2019 at "Cerebral cortex"
DOI: 10.1093/cercor/bhz114
Abstract: FOXG1 syndrome is a severe encephalopathy that exhibit intellectual disability, emotional disorder, and limited social communication. To elucidate the contribution of somatostatin-expressing interneurons (SST-INs) to the cellular basis underlying FOXG1 syndrome, here, by crossing SST-cre… read more here.
Keywords: sst; loss foxg1; foxg1 syndrome; development ... See more keywords