Articles with "foxk2" as a keyword



LncRNA SNHG7 Promotes the HCC Progression Through miR-122-5p/FOXK2 Axis

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Published in 2021 at "Digestive Diseases and Sciences"

DOI: 10.1007/s10620-021-06918-2

Abstract: Hepatocellular carcinoma (HCC) is a malignant tumor with high mortality and severe complication in China. Numerous studies have shown that long noncoding RNAs (lncRNAs) are involved in the regulation of various processes in cancer cells.… read more here.

Keywords: hcc; foxk2 axis; mir 122; foxk2 ... See more keywords

Long non-coding RNA tumor protein 53 target gene 1 promotes cervical cancer development via regulating microRNA-33a-5p to target forkhead box K2

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Published in 2022 at "Cell Cycle"

DOI: 10.1080/15384101.2022.2026705

Abstract: ABSTRACT Long non-coding RNA tumor protein 53 target gene 1 (TP53TG1) has been unraveled to exert regulatory effects on cancer progression, while the regulatory function of TP53TG1 on cervical cancer (CC) via regulating microRNA (miR)-33a-5p/Forkhead… read more here.

Keywords: via regulating; mir 33a; tp53tg1; foxk2 ... See more keywords

BLM, FOXO3, FOXK2, FOXM1, FOXR1 genes as therapeutic targets to neuroblastoma

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Published in 2018 at "Clinical Cancer Research"

DOI: 10.1158/1557-3265.tcm17-b13

Abstract: Due to heterogeneity of the neuroblastoma (NB) tumor, next-generation personalized medicine may identify therapeutic targets. Gene expression alterations of BLM (Bloom Syndrome RecQ Like Helicase) and FOX (Forkhead-box) family have been associated with an increased… read more here.

Keywords: medicine; therapeutic targets; expression; foxk2 ... See more keywords

Yiqi Yangyin Tongluo prescription targets lncRNA VIM-AS1 to regulate FOXK2/mTOR to promote autophagy and inhibit renal tubular epithelial cell apoptosis

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Published in 2025 at "Journal of Food and Drug Analysis"

DOI: 10.38212/2224-6614.3545

Abstract: Diabetic nephropathy (DN) is one dominating reason for death in diabetic patients, and its incidence is high. It has been reported that Yiqi Yangyin Tongluo prescription (YYTP) can relieve inflammation, and it owns better clinical… read more here.

Keywords: foxk2; mtor; cell apoptosis; lncrna vim ... See more keywords

FOXK2 transcription factor and its roles in tumorigenesis (Review)

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Published in 2022 at "Oncology Letters"

DOI: 10.3892/ol.2022.13581

Abstract: Forkhead box K2 (FOXK2) is a central transcriptional regulator of embryonic development and cell homeostasis. Since its discovery, evidence has shown that FOXK2 mediates a variety of biological processes involving in genomic stability, DNA repair,… read more here.

Keywords: review; foxk2; roles tumorigenesis; factor ... See more keywords

Forkhead box K2 promotes human colorectal cancer metastasis by upregulating ZEB1 and EGFR

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Published in 2019 at "Theranostics"

DOI: 10.7150/thno.31716

Abstract: Background: Metastasis is the major reason for high recurrence rates and poor survival among patients with colorectal cancer (CRC). However, the underlying molecular mechanism of CRC metastasis is unclear. This study aimed to investigate the… read more here.

Keywords: zeb1 egfr; metastasis; crc metastasis; box ... See more keywords