LAUSR

FoxO1‐AMPK‐ULK1 Regulates Ethanol‐Induced Autophagy in Muscle by Enhanced ATG14 Association with the BECN1‐PIK3C3 Complex

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1 Published in 2017 at "Alcoholism: Clinical and Experimental Research"

DOI: 10.1111/acer.13377

Abstract: BACKGROUND Excessive alcohol (EtOH) consumption causes an imbalance in protein metabolism. EtOH impairs protein synthesis in C2C12 myoblasts via a FoxO1-AMPK-TSC2-mTORC1 pathway and also induces protein degradation. As the underlying regulatory signaling cascades for these… read more here.

Keywords: pik3c3 complex; foxo1 ampk; pik3c3; becn1 ... See more keywords