Therapeutic potential of POU3F3, a novel long non-coding RNA alleviates the pathogenesis of osteoarthritis by regulating miR-29a-3p/FOXO3 axis.
Sign Up to like & getrecommendations! Published in 2022 at "Current gene therapy"
DOI: 10.2174/1566523222666220309150722
Abstract: BACKGROUND Osteoarthritis (OA) is the predominant threaten to the health of the elderly, and it is crucial to understand the molecular pathegenetic mechanisms involved in it. This study aims to investigate the role of a… read more here.
Keywords: foxo3 axis; rna; 29a foxo3; mir 29a ... See more keywords
Polymeric immunoglobulin receptor suppresses colorectal cancer through the AKT-FOXO3/4 axis by downregulating LAMB3 expression
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.924988
Abstract: Colorectal cancer (CRC) remains one of the most common malignancies worldwide and its mechanism is unclear. Polymeric immunoglobulin receptor (PIGR) which plays an important role in mucosal immunity is widely expressed in the mucosal epithelium… read more here.
Keywords: pigr; foxo3 axis; immunoglobulin receptor; polymeric immunoglobulin ... See more keywords