Melatonin protects H9c2 cardiomyoblasts from oxygen‐glucose deprivation and reperfusion‐induced injury by inhibiting Rac1/JNK/Foxo3a/Bim signaling pathway
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DOI: 10.1002/cbin.11739
Abstract: Melatonin has been shown to protect against ischemia/reperfusion (I/R)‐induced myocardial injury, however, the precise molecular mechanisms have not been fully clarified. The present study was aimed to investigate whether inactivation of Rac1/JNK/Foxo3a/Bim signaling pathway is… read more here.
Keywords: injury; melatonin; signaling pathway; foxo3a bim ... See more keywords
Influence of Melatonin on Behavioral and Neurological Function of Rats with Focal Cerebral Ischemia-Reperfusion Injury via the JNK/FoxO3a/Bim Pathway
Sign Up to like & getrecommendations! Published in 2022 at "Computational and Mathematical Methods in Medicine"
DOI: 10.1155/2022/8202975
Abstract: Objective To investigate the influence of melatonin on behavioral and neurological function of rats with focal cerebral ischemia-reperfusion injury via the JNK/FoxO3a/Bim pathway. Methods One hundred and twenty healthy male SD rats were randomized into… read more here.
Keywords: jnk foxo3a; group; foxo3a bim; model ... See more keywords
Effects of fine particulate PM2.5 on emphysema of mice via regulating FOXO3A/BIM axis.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of biological regulators and homeostatic agents"
DOI: 10.23812/20-50-a-54
Abstract: This study aims to investigate the role of PM2.5 exposure in inducing apoptosis of alveolar epithelial cells and thereafter emphysema in mice, and the underlying mechanism. PM2.5 exposure model in mice was constructed. Lung tissues… read more here.
Keywords: foxo3a bim; a549 cells; emphysema mice; bim ... See more keywords