High inter‐follicular spatial co‐localization of CD8+FOXP3+ with CD4+CD8+ cells predicts favorable outcome in follicular lymphoma
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DOI: 10.1002/hon.3003
Abstract: The spatial architecture of the lymphoid tissue in follicular lymphoma (FL) presents unique challenges to studying its immune microenvironment. We investigated the spatial interplay of T cells, macrophages, myeloid cells and natural killer T cells… read more here.
Keywords: inter follicular; foxp3 cd4; follicular lymphoma; cd8 foxp3 ... See more keywords
Clinical implications of the tumor microenvironment using multiplexed immunohistochemistry in patients with advanced or metastatic renal cell carcinoma treated with nivolumab plus ipilimumab
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DOI: 10.3389/fonc.2022.969569
Abstract: Purpose Immune checkpoint inhibitors (ICIs) such as nivolumab and ipilimumab (N/I) are important treatment options for advanced renal cell carcinoma (RCC). The tumor microenvironment (TME) in these ICI-treated patients is largely unknown. Methods Twenty-four patients… read more here.
Keywords: foxp3 cd4; cell carcinoma; cell; renal cell ... See more keywords