FOXP3+ T cells are present in kidney biopsy samples in children with tubulointerstitial nephritis and uveitis syndrome
Sign Up to like & getrecommendations! Published in 2017 at "Pediatric Nephrology"
DOI: 10.1007/s00467-017-3796-z
Abstract: BackgroundTubulointerstitial nephritis (TIN) is an inflammatory disease of unknown pathogenesis. To evaluate a possible role of regulatory T cells (Tregs) in the pathophysiology of TIN with (TINU) and without uveitis, we investigated the presence and… read more here.
Keywords: kidney biopsy; present kidney; foxp3 cells; cells present ... See more keywords
HIGH EXPRESSION WITH PD-1+ FOXP3+ ΓΔ T REGULATORY SUBSETS IN CHRONIC MYELOID LEUKEMIA PATIENTS
Sign Up to like & getrecommendations! Published in 2019 at "Experimental Hematology"
DOI: 10.1016/j.exphem.2019.06.462
Abstract: Objective Tyrosine kinase inhibitor (TKI) has achieved certain efficacy in treatment of chronic myeloid leukemia (CML), but there are still many cases of drug resistance and relapse. Anti-leukemia immunity of γδ T cells may play… read more here.
Keywords: expression; leukemia; cml patients; regulatory subsets ... See more keywords
Elevated level of circulating CD4+Helios+FoxP3+ cells in primary Sjogren’s syndrome patients
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DOI: 10.1080/14397595.2016.1226470
Abstract: Abstract Objective: This study was designed to investigate the expression of regulatory T cells in primary Sjögren’s Syndrome (pSS) and to evaluate the clinical role of CD4 + Helios+ FoxP3+ cells in pSS patients. Methods: CD4 + FoxP3+ T cells in… read more here.
Keywords: elevated level; helios foxp3; pss patients; foxp3 cells ... See more keywords
Plasmacytoid Dendritic Cell–driven Induction of Treg Is Strain Specific and Correlates With Spontaneous Acceptance of Kidney Allografts
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DOI: 10.1097/tp.0000000000002867
Abstract: Background. DBA/2J kidney allografts, but not heart allografts, are spontaneously accepted indefinitely in C57BL/6 (B6) mice, through regulatory tolerance mechanism dependent on Foxp3+ cells. In contrast, B6 kidneys are rejected within a week in DBA/2J… read more here.
Keywords: kidney allografts; cell; strain; induction ... See more keywords
Increased circulating CD4+FOXP3+ T cells associate with early relapse following autologous hematopoietic stem cell transplantation in multiple myeloma patients
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DOI: 10.18632/oncotarget.25553
Abstract: We investigated dynamics of CD4+FOXP3+ T cell recovery following the high-dose chemotherapy (HDC) with autologous hematopoietic stem cell transplantation (auto-HSCT) in multiple myeloma (MM) patients. Circulating CD4+FOXP3+ T cells of 79 MM patients were evaluated… read more here.
Keywords: auto hsct; cd4 foxp3; circulating cd4; foxp3 cells ... See more keywords
IL-1β-MyD88-mTOR Axis Promotes Immune-Protective IL-17A+Foxp3+ Cells During Mucosal Infection and Is Dysregulated With Aging
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DOI: 10.3389/fimmu.2020.595936
Abstract: CD4+Foxp3+Tregs maintain immune homeostasis, but distinct mechanisms underlying their functional heterogeneity during infections are driven by specific cytokine milieu. Here we show that MyD88 deletion in Foxp3+ cells altered their function and resulted in increased… read more here.
Keywords: foxp3 cells; foxp3; oral mucosa; cd4 ... See more keywords
Increased PD-1+Foxp3+ γδ T cells associate with poor overall survival for patients with acute myeloid leukemia
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DOI: 10.3389/fonc.2022.1007565
Abstract: Problems γδ T cells are essential for anti-leukemia function in immunotherapy, however, γδ T cells have different functional subsets, including regulatory cell subsets expressing the Foxp3. Whether they are correlated with immune-checkpoint mediated T cell… read more here.
Keywords: cell; leukemia; acute myeloid; foxp3 cells ... See more keywords