Association of FOXP3 and GAGE10 Promoter Polymorphisms and Decreased FOXP3 Expression in Regulatory T cells with Susceptibility to Generalized Vitiligo in Gujarat Population.
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DOI: 10.1016/j.gene.2020.145295
Abstract: Alterations in regulatory T (Treg) cells have been observed in generalized vitiligo (GV) patients and decreased Forkhead Box P3 (FOXP3) has been implicated in the disease pathogenesis. The present study examined FOXP3 rs3761547(A>G), rs3761548(C>A), rs2232365(A>G)… read more here.
Keywords: protein; generalized vitiligo; gujarat population; foxp3 ... See more keywords
FOXP3 mRNA Profile Prognostic of Acute T Cell–mediated Rejection and Human Kidney Allograft Survival
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DOI: 10.1097/tp.0000000000003478
Abstract: Supplemental Digital Content is available in the text. Background. T cell–mediated rejection (TCMR) is the most frequent type of acute rejection and is associated with kidney allograft failure. Almost 40% of TCMR episodes are nonresponsive… read more here.
Keywords: allograft; kidney allograft; foxp3 mrna; cell ... See more keywords
Evaluation of urinary FOXP3 mRNA as a biomarker of lupus nephritis in Egyptian patients with systemic lupus erythematosus
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DOI: 10.1177/09612033211030559
Abstract: Aim Lupus nephritis (LN) is one of the most serious complications of SLE. Tregs (Regulatory T lymphocytes) are thought to play a part in the pathogenesis of SLE. According to recent research, Foxp3, a Treg… read more here.
Keywords: foxp3 mrna; foxp3; urinary foxp3; lupus nephritis ... See more keywords
Metformin improves FOXP3 mRNA expression through suppression of interferon gamma levels in pristane-induced murine models of lupus.
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DOI: 10.12688/f1000research.23471.1
Abstract: Background: A recent study has indicated the potential of metformin therapy for lupus in animal models, but there has been no study evaluating the effect on pristane-induced lupus. This study aims to evaluate the effect… read more here.
Keywords: oral metformin; foxp3 mrna; mrna expression; pristane induced ... See more keywords