Dysregulation of humoral immunity in Foxp3 conditional-knockout mice.
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DOI: 10.1016/j.bbrc.2019.04.090
Abstract: Foxp3+ regulatory T cells (Tregs) are crucial for maintaining tolerance to self-antigens and preventing autoimmune diseases. Loss of Foxp3 expression leads to autoimmunity and disrupts humoral immune responses, including hyperproduction of immunoglobulin E (IgE). Elucidation… read more here.
Keywords: foxp3floxr26creert2 mice; humoral immunity; knockout mice; mice ... See more keywords