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   Articles with "foxr2" as a keyword



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Somatic LINE-1 promoter acquisition drives oncogenic FOXR2 activation in pediatric brain tumor

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recommendations! Published in 2022 at "Acta Neuropathologica"

DOI: 10.1007/s00401-022-02420-9

Abstract: Long Interspersed Element-1 (LINE-1 or L1) is the only autonomously active human retrotransposable element shown to mobilize in cancers, which can disrupt normal gene function or regulation [6]. However, L1 regulatory elements have not been… read more here.

Keywords: online resource; tumor; insertion; foxr2 ... See more keywords
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DIPG-22. DISSECTING THE ONCOGENIC ROLE OF FOXR2 IN DIFFUSE INTRINSIC PONTINE GLIOMA

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recommendations! Published in 2020 at "Neuro-Oncology"

DOI: 10.1093/neuonc/noaa222.072

Abstract: Abstract BACKGROUND Diffuse intrinsic pontine gliomas (DIPGs) pose particular challenges for treatment. We recently completed a genomic analysis of close to 200 DIPGs and high-grade gliomas. We identified that nearly 10% of all DIPGs have… read more here.

Keywords: dipg; diffuse intrinsic; foxr2; intrinsic pontine ... See more keywords
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FoxR2 promotes glioma proliferation by suppression of the p27 pathway

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recommendations! Published in 2017 at "Oncotarget"

DOI: 10.18632/oncotarget.17447

Abstract: FoxR2 plays an important role in the development of many human tumors. However, the effects of FoxR2 on tumorigenicity of human glioma remain unclear. In this study, we investigated the roles of FoxR2 in cell… read more here.

Keywords: foxr2; promotes glioma; proliferation; foxr2 promotes ... See more keywords
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FOXR2 Promotes the Proliferation, Invasion, and Epithelial-Mesenchymal Transition in Human Colorectal Cancer Cells.

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recommendations! Published in 2017 at "Oncology research"

DOI: 10.3727/096504016x14771034190471

Abstract: Forkhead box R2 (FOXR2), a member of the FOX gene family, has not been very well investigated for its role in cancer. A recent study has shown that FOXR2 is highly expressed in breast cancer… read more here.

Keywords: foxr2; proliferation invasion; colorectal cancer; crc ... See more keywords