Oxidized LDL-induced FOXS1 mediates cholesterol transport dysfunction and inflammasome activation to drive aortic valve calcification
Sign Up to like & getrecommendations! Published in 2025 at "Cardiovascular Research"
DOI: 10.1093/cvr/cvaf159
Abstract: Abstract Aims Calcific aortic valve disease (CAVD) is becoming more prevalent with the population ageing; however, there is currently no medical therapy available. During early lipid deposition, low-density lipoprotein (LDL) mediates chronic inflammation and accelerates… read more here.
Keywords: valve; cholesterol transport; foxs1; aortic valve ... See more keywords
Pan-Cancer Analysis Predicts FOXS1 as a Key Target in Prognosis and Tumor Immunotherapy
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of General Medicine"
DOI: 10.2147/ijgm.s354195
Abstract: Purpose Only a few studies have reported the role of FOXS1, a transcriptional factor, in the tumor development process. In this article, we investigate the function of FOXS1 in distinct neoplastic development and the tumor… read more here.
Keywords: tumor immunotherapy; cancer; foxs1; tumor ... See more keywords