Structure-Based Optimization of Protease-Inhibitor Interactions to Enhance Specificity of Human Stefin-A against Falcipain-2 from the Plasmodium falciparum 3D7 Strain.
Sign Up to like & getrecommendations! Published in 2023 at "Biochemistry"
DOI: 10.1021/acs.biochem.2c00585
Abstract: The emergence of resistance in Plasmodium falciparum to frontline artemisinin-based combination therapies has raised global concerns and emphasized the identification of new drug targets for malaria. Cysteine protease falcipain-2 (FP2), involved in host hemoglobin degradation… read more here.
Keywords: plasmodium falciparum; structure; human stefin; stfa ... See more keywords
Carbon nanodot-based heterostructures for improving the charge separation and the photocurrent generation.
Sign Up to like & getrecommendations! Published in 2019 at "Nanoscale"
DOI: 10.1039/c9nr00951e
Abstract: The possibility to employ carbon nanodots (CNDs) in solar devices was exploited by combining them with a fulleropyrrolidine derivative (FP2). The interaction between the two species was promoted by the presence of opposite electrostatic charges… read more here.
Keywords: carbon; fp2; charge; fp2 cnds ... See more keywords