6-Furopyridine Hexamethylene Amiloride Is a Non-Selective P2X7 Receptor Antagonist
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DOI: 10.3390/biom12091309
Abstract: P2X7 is an extracellular adenosine 5′-triphopshate (ATP)-gated cation channel present on leukocytes, where its activation induces pro-inflammatory cytokine release and ectodomain shedding of cell surface molecules. Human P2X7 can be partially inhibited by amiloride and… read more here.
Keywords: hexamethylene amiloride; p2x7; hek293 cells; fphma ... See more keywords