Synthesis of Polyene Bioactive Natural Products: FR252921 and Vitamin A.
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DOI: 10.1021/acs.orglett.2c00546
Abstract: A formal synthesis of FR252921, a potent macrocyclic immunosuppressive agent, and a six-step synthesis of vitamin A have been demonstrated. The application of a ruthenium-catalyzed step-economic and environmentally benign strategy for the highly stereo- and… read more here.
Keywords: natural products; synthesis polyene; synthesis; fr252921 vitamin ... See more keywords