Vertebral Fracture Assessment Increases Use of Pharmacologic Therapy for Fracture Prevention in Clinical Practice
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Bone and Mineral Research"
DOI: 10.1002/jbmr.3836
Abstract: The impact of vertebral fracture assessment (VFA) on lateral spine images in clinical practice on subsequent patient use of fracture prevention medication is unknown. Our objective was to determine the association of prevalent vertebral fracture… read more here.
Keywords: vfa; fracture prevention; fracture; bone ... See more keywords
A Bone-Penetrating Precise Controllable Drug Release System Enables Localized Treatment of Osteoporotic Fracture Prevention via Modulating Osteoblast-Osteoclast Communication.
Sign Up to like & getrecommendations! Published in 2023 at "Small"
DOI: 10.1002/smll.202207195
Abstract: Improving local bone mineral density (BMD) at fracture-prone sites of bone is a clinical concern for osteoporotic fracture prevention. In this study, a featured radial extracorporeal shock wave (rESW) responsive nano-drug delivery system (NDDS) is… read more here.
Keywords: fracture; fracture prevention; bone; osteoclast communication ... See more keywords
Detection of vertebral fracture in an acute hospital setting: an intervention to reduce future fracture risk through fracture liaison service intervention?
Sign Up to like & getrecommendations! Published in 2020 at "Archives of Osteoporosis"
DOI: 10.1007/s11657-020-00832-2
Abstract: Summary We introduced a standardised reporting system in the radiology department to highlight vertebral fractures and to signpost fracture prevention services. Our quality improvement project achieved improved fracture reporting, access to the FLS service, bone… read more here.
Keywords: intervention; fracture prevention; fracture; fracture liaison ... See more keywords
Clinical Importance of Bone Matrix Damage Mechanisms for Fracture Prevention
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DOI: 10.1007/s11914-021-00678-8
Abstract: Bone matrix exhibits great complexity in its composition, structure and mechanics. Here, we provide a review of recent research articles and appraise the evidence that bone matrix quality is clinically important and possibly targetable for… read more here.
Keywords: fracture prevention; matrix; bone matrix; bone ... See more keywords
Osteoporosis: Teriparatide preferable for fracture prevention
Sign Up to like & getrecommendations! Published in 2018 at "Nature Reviews Rheumatology"
DOI: 10.1038/nrrheum.2017.194
Abstract: A stepwise dose increase of febuxostat was comparable to prophylactic low-dose colchicine for reducing flares in an open-label, randomized study of 241 patients with gout. Flares occurred in 20.8% of patients taking stepped-up (10 mg… read more here.
Keywords: fracture prevention; patients taking; daily febuxostat; teriparatide preferable ... See more keywords
Osteoporosis in patients with rheumatoid arthritis: an update in epidemiology, pathogenesis, and fracture prevention
Sign Up to like & getrecommendations! Published in 2020 at "Expert Opinion on Pharmacotherapy"
DOI: 10.1080/14656566.2020.1787381
Abstract: ABSTRACT Introduction Rheumatoid arthritis (RA) is a chronic disabling disease characterized by a symmetrical articular involvement due to ongoing joint inflammation, if left insufficiently treated. Local and generalized bone loss is one of the main… read more here.
Keywords: risk; fracture prevention; epidemiology; bone loss ... See more keywords
Introducing the American Society for Bone and Mineral Research multistakeholder group secondary fracture prevention recommendations: Nurse practitioners play an important role
Sign Up to like & getrecommendations! Published in 2021 at "Journal of the American Association of Nurse Practitioners"
DOI: 10.1097/jxx.0000000000000616
Abstract: ABSTRACT Sequelae after an osteoporosis-related fracture include significant morbidity and mortality. Preventing repeat fractures is an important aspect of mitigating these sequelae. As highlighted in the American Society for Bone and Mineral Research multistakeholder coalition's… read more here.
Keywords: american society; nurse practitioners; fracture; secondary fracture ... See more keywords
Improving uptake of Fracture Prevention drug treatments: a protocol for Development of a consultation intervention (iFraP-D)
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DOI: 10.1136/bmjopen-2021-048811
Abstract: Introduction Prevention of fragility fractures, a source of significant economic and personal burden, is hindered by poor uptake of fracture prevention medicines. Enhancing communication of scientific evidence and elicitation of patient medication-related beliefs has the… read more here.
Keywords: intervention; fracture prevention; uptake fracture; ifrap ... See more keywords
Rethinking the Appraisal and Approval of Drugs for Fracture Prevention
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DOI: 10.3389/fphar.2017.00265
Abstract: Background: In January 2014, the EMA's Pharmacovigilance Risk Assessment Committee recommended that strontium ranelate no longer be used for osteoporosis. However, EMA's Committee for Medicinal Products for Human Use decided to restrict its use rather… read more here.
Keywords: fracture prevention; drugs fracture; harm benefit; rethinking appraisal ... See more keywords