Risperidone versus aripiprazole fracture risk in children and adolescents with autism spectrum disorders
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DOI: 10.1002/aur.2541
Abstract: Risperidone and aripiprazole, commonly used antipsychotics in children with autism spectrum disorder (ASD), have previously been associated with elevated fracture risk in other populations. The aim of this study was to evaluate and compare the… read more here.
Keywords: risk; aripiprazole risperidone; fracture; fracture risk ... See more keywords
Prediabetes and osteoporotic fracture risk: A meta‐analysis of prospective cohort studies
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DOI: 10.1002/dmrr.3568
Abstract: Diabetes confers an increased risk of fracture. However, whether prediabetes is also a risk factor of osteoporotic fracture has not been comprehensively examined. We performed a meta‐analysis to evaluate the relationship between prediabetes and osteoporotic… read more here.
Keywords: fracture; meta analysis; fracture risk; prediabetes osteoporotic ... See more keywords
Fracture Risk After Bariatric Surgery: Roux‐en‐Y Gastric Bypass Versus Adjustable Gastric Banding
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DOI: 10.1002/jbmr.3101
Abstract: The long‐term consequences of bariatric surgery on fracture risk are unclear but are likely to vary by procedure type. In physiologic studies, Roux‐en‐Y gastric bypass (RYGB) and adjustable gastric banding (AGB) have differential effects on… read more here.
Keywords: risk; fracture; bariatric surgery; fracture risk ... See more keywords
27‐Hydroxycholesterol, an Endogenous SERM, and Risk of Fracture in Postmenopausal Women: A Nested Case‐Cohort Study in the Women's Health Initiative
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Bone and Mineral Research"
DOI: 10.1002/jbmr.3576
Abstract: 27‐Hydroxycholesterol (27HC) is a purported, novel endogenous SERM. In animal models, 27HC has an anti‐estrogen effect in bone, and 17β‐estradiol mitigates this effect. 27HC in relation to fracture risk has not been investigated in humans.… read more here.
Keywords: risk; fracture; risk fracture; fracture risk ... See more keywords
One Year of Romosozumab Followed by Two Years of Denosumab Maintains Fracture Risk Reductions: Results of the FRAME Extension Study
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Bone and Mineral Research"
DOI: 10.1002/jbmr.3622
Abstract: Romosozumab, a humanized monoclonal antibody that binds and inhibits sclerostin, has the dual effect of increasing bone formation and decreasing bone resorption. As previously reported in the pivotal FRActure study in postmenopausal woMen with ostEoporosis… read more here.
Keywords: fracture; study; bone; fracture risk ... See more keywords
Post‐fracture Risk Assessment: Target the Centrally Sited Fractures First! A Substudy of NoFRACT
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Bone and Mineral Research"
DOI: 10.1002/jbmr.3827
Abstract: The location of osteoporotic fragility fractures adds crucial information to post‐fracture risk estimation. Triaging patients according to fracture site for secondary fracture prevention can therefore be of interest to prioritize patients considering the high imminent… read more here.
Keywords: risk; bone mineral; fracture; fracture risk ... See more keywords
Acetylcholinesterase Inhibitors Are Associated with Reduced Fracture Risk among Older Veterans with Dementia
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Bone and Mineral Research"
DOI: 10.1002/jbmr.3916
Abstract: Acetylcholinesterase inhibitors (AChEIs) have been noted to increase bone density and quality in mice. Human studies are limited but suggest an association with improved bone healing after hip fracture. We examined the relationship between AChEI… read more here.
Keywords: older veterans; risk; fracture; acetylcholinesterase inhibitors ... See more keywords
T‐Score as an Indicator of Fracture Risk During Treatment With Romosozumab or Alendronate in the ARCH Trial
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Bone and Mineral Research"
DOI: 10.1002/jbmr.3996
Abstract: In the Active‐Controlled Fracture Study in Postmenopausal Women With Osteoporosis at High Risk (ARCH) clinical trial (NCT01631214), 1 year of romosozumab followed by alendronate reduced the risk of vertebral and nonvertebral fractures compared to alendronate alone… read more here.
Keywords: romosozumab; fracture; year; fracture risk ... See more keywords
The Vitamin D Metabolite Ratio Is Associated With Changes in Bone Density and Fracture Risk in Older Adults
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Bone and Mineral Research"
DOI: 10.1002/jbmr.4426
Abstract: Recent studies have suggested that 25‐hydroxyvitamin D (25(OH)D) may be a poor biomarker of bone health, in part because measured levels incorporate both protein‐bound and free vitamin D. The ratio of its catabolic product (24,25‐dihydroxyvitamin… read more here.
Keywords: older adults; bone; fracture risk; vmr ... See more keywords
Potential Adverse Effect of Nonsteroidal Anti‐Inflammatory Drugs (NSAIDs) on Bisphosphonate Efficacy: An Exploratory Post Hoc Analysis From a Randomized Controlled Trial of Clodronate
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Bone and Mineral Research"
DOI: 10.1002/jbmr.4548
Abstract: Nonsteroidal anti‐inflammatory drugs (NSAIDs) have been reported to have weak but beneficial effects on bone health, including fracture risk, but many epidemiological studies are likely confounded. We explored the relationship between NSAIDs and fracture risk… read more here.
Keywords: nonsteroidal anti; clodronate; fracture risk; risk ... See more keywords
Identifying Causes of Fracture Beyond Bone Mineral Density: Evidence From Human Genetics
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Bone and Mineral Research"
DOI: 10.1002/jbmr.4632
Abstract: New therapies may help to prevent osteoporotic fractures other than through increasing bone mineral density (BMD). Because fracture risk has an important genetic component, we aim to identify loci increasing fracture risk that do not… read more here.
Keywords: fracture; fracture risk; risk; non bmd ... See more keywords