The Fragile X Protein Disordered Regions Bind a Novel RNA Target.
Sign Up to like & getrecommendations! Published in 2022 at "Biochemistry"
DOI: 10.1021/acs.biochem.2c00228
Abstract: The fragile X proteins (FXPs) are a family of RNA-binding proteins that regulate mRNA translation to promote proper neural development and cognition in mammals. Of particular interest to researchers is the fragile X mental retardation… read more here.
Keywords: fragile protein; rna target; protein disordered; target ... See more keywords
A serum microRNA sequence reveals fragile X protein pathology in amyotrophic lateral sclerosis
Sign Up to like & getrecommendations! Published in 2021 at "Brain"
DOI: 10.1093/brain/awab018
Abstract: Abstract Knowledge about converging disease mechanisms in the heterogeneous syndrome amyotrophic lateral sclerosis (ALS) is rare, but may lead to therapies effective in most ALS cases. Previously, we identified serum microRNAs downregulated in familial ALS,… read more here.
Keywords: serum; pathology; amyotrophic lateral; fragile protein ... See more keywords