Distinct social attention profiles in preschoolers with autism contrasted to fragile X syndrome
Sign Up to like & getrecommendations! Published in 2022 at "Autism Research"
DOI: 10.1002/aur.2857
Abstract: Social attention is a critical skill for learning and development. Social attention difficulties are present in both non‐syndromic autism spectrum disorder (nsASD) and fragile X syndrome (FXS), and our understanding of these difficulties is complicated… read more here.
Keywords: eye contact; social attention; social scene; attention ... See more keywords
Alterations in CA1 hippocampal synapses in a mouse model of fragile X syndrome
Sign Up to like & getrecommendations! Published in 2018 at "Glia"
DOI: 10.1002/glia.23284
Abstract: Fragile X Syndrome (FXS) is the major cause of inherited mental retardation and the leading genetic cause of Autism spectrum disorders. FXS is caused by mutations in the Fragile X Mental Retardation 1 (Fmr1) gene,… read more here.
Keywords: fmr1 mice; ca1 hippocampal; fragile syndrome; microscopy ... See more keywords
Dysregulated cholesterol metabolism, aberrant excitability and altered cell cycle of astrocytes in fragile X syndrome
Sign Up to like & getrecommendations! Published in 2023 at "Glia"
DOI: 10.1002/glia.24331
Abstract: Fragile X syndrome (FXS), the most prevalent heritable form of intellectual disability, is caused by the transcriptional silencing of the FMR1 gene. While neuronal contribution to FXS has been extensively studied in both animal and… read more here.
Keywords: fxs; fragile syndrome; cell cycle;
Cerebellum neuropathology and motor skill deficits in fragile X syndrome
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Developmental Neuroscience"
DOI: 10.1002/jdn.10217
Abstract: Fragile X syndrome (FXS) is a leading form of inherited intellectual disability and single‐gene cause of autism spectrum disorder (ASD) and is characterized by core deficits in cognitive flexibility, sensory sensitivity, emotion, and social interactions.… read more here.
Keywords: skill deficits; motor skill; fxs; motor ... See more keywords
Descriptive analysis of seizures and comorbidities associated with fragile X syndrome
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Genetics & Genomic Medicine"
DOI: 10.1002/mgg3.2001
Abstract: Fragile X syndrome is characterized by a myriad of physical features, behavioral features, and medical problems. Commonly found behavioral features are hyperactivity, anxiety, socialization difficulties, and ASD. There is also a higher incidence than in… read more here.
Keywords: fragile syndrome; descriptive analysis; analysis seizures; associated fragile ... See more keywords
Height and BMI in fragile X syndrome: A longitudinal assessment
Sign Up to like & getrecommendations! Published in 2022 at "Obesity"
DOI: 10.1002/oby.23368
Abstract: Previously reported data regarding growth parameters in individuals with fragile X syndrome (FXS) are inconsistent. A longitudinal analysis of height and BMI in a large number of individuals with FXS was conducted. read more here.
Keywords: syndrome longitudinal; longitudinal assessment; fragile syndrome; height bmi ... See more keywords
Fragile X Syndrome: Introduction.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-9080-1_1
Abstract: Fragile X syndrome (FXS) is one of the most common reasons for intellectual disability (ID). First described in the 1940s, it took many years to understand the disease. The awe-inspiring breakthroughs in both science and… read more here.
Keywords: syndrome introduction; biology; fragile syndrome;
Clinical Genetic Testing for Fragile X Syndrome by Polymerase Chain Reaction Amplification and Southern Blot Analyses.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-9080-1_2
Abstract: Fragile X syndrome (FXS) is characterized by mental retardation and in the vast majority of cases it is caused by expansion of CGG trinucleotide repeats in the 5' untranslated region (or UTR) in the FMR1 gene… read more here.
Keywords: genetic testing; fragile syndrome; clinical genetic; chain reaction ... See more keywords
Prevalence and Predictors of Anxiety Disorders in Adolescent and Adult Males with Autism Spectrum Disorder and Fragile X Syndrome
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Autism and Developmental Disorders"
DOI: 10.1007/s10803-018-3804-6
Abstract: Anxiety disorders affect ~ 15–20% of youths without neurodevelopmental disorders, with persons having autism spectrum disorder (ASD) and fragile X syndrome (FXS) at elevated risk for anxiety disorders. Few studies have compared rates and predictors of… read more here.
Keywords: fragile syndrome; anxiety; spectrum disorder; anxiety disorders ... See more keywords
Rethinking Measurement Standards of Autism Symptomology in Adolescents with Fragile X Syndrome.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of autism and developmental disorders"
DOI: 10.1007/s10803-021-04892-2
Abstract: Accurate representation of autism spectrum disorder (ASD) in fragile X syndrome (FXS) is necessary for the field. We examined classifications of ASD using three approaches-Autism Diagnostic Observation Schedule (ADOS-2; Lord et al. 2012), Childhood Autism… read more here.
Keywords: measurement standards; fragile syndrome; autism; rethinking measurement ... See more keywords
Empathy and Anxiety in Young Girls with Fragile X Syndrome.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of autism and developmental disorders"
DOI: 10.1007/s10803-021-05105-6
Abstract: We tested whether empathy is impaired and associated with anxiety in girls with fragile X syndrome (FXS). We measured parent-reported empathy and self-reported anxiety in young girls with FXS and in a developmentally-matched comparison group.… read more here.
Keywords: girls fxs; fragile syndrome; anxiety; anxiety young ... See more keywords