Covalent fragment inhibits intramembrane proteolysis
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2022.958399
Abstract: Alzheimer’s disease (AD) is a serious public health crisis with only one current modifying treatment. The reduction of amyloid load by targeting γ-secretase (GS) has been a leading approach in AD drug discovery and development.… read more here.
Keywords: fragment inhibits; covalent fragment; intramembrane proteolysis; inhibits intramembrane ... See more keywords