SV40 T antigen helicase domain regions responsible for oligomerisation regulate Okazaki fragment synthesis initiation
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DOI: 10.1002/2211-5463.13373
Abstract: The initiation of Okazaki fragment synthesis during cellular DNA replication is a crucial step for lagging strand synthesis, which is carried out by the primase function of DNA polymerase α‐primase (Pol‐prim). Since cellular replication protein… read more here.
Keywords: fragment synthesis; okazaki fragment; synthesis; rpa ... See more keywords
Modular Fragment Synthesis and Bioinformatic Analysis Propose a Revised Vancoresmycin Stereoconfiguration.
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DOI: 10.1021/acs.orglett.0c03957
Abstract: Elaborate fragments of the proposed stereostructure of the complex polyketide antibiotic vancoresmycin have been synthesized in a stereoselective fashion based on a modular and convergent approach. Significant nuclear magnetic resonance differences in one of these… read more here.
Keywords: stereoconfiguration; analysis; synthesis bioinformatic; modular fragment ... See more keywords