Articles with "fragment variable" as a keyword



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Designing and generating a single-chain fragment variable (scFv) antibody against IL2Rα (CD25): An in silico and in vitro study

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Published in 2021 at "Iranian Journal of Basic Medical Sciences"

DOI: 10.22038/ijbms.2021.51709.11728

Abstract: Objective(s): IL-2Rα plays a critical role in maintaining immune function. However, expression and secretion of CD25 in various malignant disorders and autoimmune diseases are now well established. Thus, CD25 is considered an important target candidate… read more here.

Keywords: fragment variable; chain fragment; anti cd25; scfv ... See more keywords
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Single-Chain Fragment Variable: Recent Progress in Cancer Diagnosis and Therapy

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Published in 2022 at "Cancers"

DOI: 10.3390/cancers14174206

Abstract: Simple Summary Recombinant antibody fragments have shown remarkable potential as diagnostic and therapeutic tools in the fight against cancer. The single-chain fragment variable (scFv) that contains the complete antigen-binding domains of a whole antibody, has… read more here.

Keywords: fragment variable; single chain; chain fragment; cancer ... See more keywords