Quadruple Target Evaluation of Diversity-Optimized Halogen-Enriched Fragments (HEFLibs) Reveals Substantial Ligand Efficiency for AP2-Associated Protein Kinase 1 (AAK1)
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DOI: 10.3389/fchem.2021.815567
Abstract: Fragment-based drug discovery is one of the most utilized approaches for the identification of novel weakly binding ligands, by efficiently covering a wide chemical space with rather few compounds and by allowing more diverse binding… read more here.
Keywords: fragments heflibs; protein kinase; enriched fragments; halogen ... See more keywords