Isatuximab plus pomalidomide and dexamethasone in frail patients with relapsed/refractory multiple myeloma: ICARIA‐MM subgroup analysis
Sign Up to like & getrecommendations! Published in 2021 at "American Journal of Hematology"
DOI: 10.1002/ajh.26319
Abstract: die of BM failure. This similarity to MDS-Mut in clinical presentation and natural history raises the possibility that MDS-NDM cases may harbor mutations in genes not covered in standard sequencing panels, or not detected in… read more here.
Keywords: frail patients; dexamethasone frail; pomalidomide dexamethasone; plus pomalidomide ... See more keywords
Trends in HbA1c thresholds for initiation of hypoglycemic agents: Impact of changed recommendations for older and frail patients
Sign Up to like & getrecommendations! Published in 2020 at "Pharmacoepidemiology and Drug Safety"
DOI: 10.1002/pds.5129
Abstract: Less strict glycated hemoglobin (HbA1c) thresholds have been recommended in older and/or frail type 2 diabetes (T2D) patients than in younger and less frail patients for initiating hypoglycemic agents since 2011. We aimed to assess… read more here.
Keywords: frail patients; trends hba1c; hypoglycemic agents; thresholds initiation ... See more keywords
Cardiac surgery improves the postoperative frailty score of frail patients
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Anesthesia"
DOI: 10.1007/s00540-021-03025-4
Abstract: Background Cardiac surgery in frail patients has been reported to be associated with increased mortality and morbidity but may improve functional status of frail patients. Few studies have investigated the impact of cardiac surgery on… read more here.
Keywords: kcl score; cardiac surgery; frailty; frail patients ... See more keywords
The efficacy of adjuvant chemotherapy for resected high-risk stage II and stage III colorectal cancer in frail patients
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Clinical Oncology"
DOI: 10.1007/s10147-021-01876-1
Abstract: The number of frail patients with colorectal cancer (CRC) has increased. Despite evidence-based treatment guidelines, a large proportion of patients with resected CRC do not receive adjuvant chemotherapy in daily practice. This retrospective study aimed… read more here.
Keywords: frail patients; stage; frailty; adjuvant chemotherapy ... See more keywords
Co-induction with a vasopressor "chaser" to mitigate propofol-induced hypotension when intubating critically ill/frail patients-A questionable practice.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of critical care"
DOI: 10.1016/j.jcrc.2019.09.015
Abstract: Prophylactic administration of a vasopressor to mitigate the hypotensive effect of propofol (and/or other co-induction agents) during sedation/anesthesia immediately prior to tracheal intubation in frail patients in the intensive care unit and emergency and operating… read more here.
Keywords: propofol; frail patients; hypotension; practice ... See more keywords
Management and supportive treatment of frail patients with metastatic pancreatic cancer.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of geriatric oncology"
DOI: 10.1016/j.jgo.2018.06.005
Abstract: Data regarding management of frail patients with pancreatic ductal adenocarcinoma practice is currently very scarce. Randomized clinical trials usually exclude these subgroup of patients and the majority of the publications only consider chronological age and… read more here.
Keywords: management; supportive treatment; management supportive; frail patients ... See more keywords
Analysis of readmissions data among frail and non-frail patients presenting for acoustic neuroma
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Neuroscience"
DOI: 10.1016/j.jocn.2022.03.013
Abstract: The incidence of acoustic neuromas in the United States is 1.09 per 100,000 with 23,739 newly diagnosed cases in the years 2004 to 2010. Because the recent literature has supported that frailty can serve as… read more here.
Keywords: frail non; frail patients; acoustic neuroma; non frail ... See more keywords
Con: Can We Influence Postoperative Outcomes of Frail Patients After Cardiac Surgery?
Sign Up to like & getrecommendations! Published in 2023 at "Journal of cardiothoracic and vascular anesthesia"
DOI: 10.1053/j.jvca.2023.03.003
Abstract: Frail patients are scheduled routinely for elective cardiovascular surgery. Despite the proven association between frailty and postoperative outcomes, currently, there is no consistent evidence that the preoperative optimization of frail patients with preoperative nutrition support… read more here.
Keywords: outcomes frail; influence postoperative; frail patients; surgery ... See more keywords
Comparative effectiveness of radical cystectomy and radiotherapy without chemotherapy in frail patients with bladder cancer
Sign Up to like & getrecommendations! Published in 2020 at "Scandinavian Journal of Urology"
DOI: 10.1080/21681805.2019.1711160
Abstract: Abstract Objectives: To evaluate cancer-specific (CSS) and overall survival (OS) in a group of frail patients who were treated with RT without chemotherapy and to compare them with a matched cohort of patients treated with… read more here.
Keywords: chemotherapy; bladder cancer; patients treated; frail patients ... See more keywords
Effect of frailty on outcomes of endovascular treatment for acute ischaemic stroke in older patients.
Sign Up to like & getrecommendations! Published in 2022 at "Age and ageing"
DOI: 10.1093/ageing/afac096
Abstract: BACKGROUND frailty has been shown to be a better predictor of clinical outcomes than age alone across many diseases. Few studies have examined the relationship between frailty, stroke and stroke interventions such as endovascular thrombectomy… read more here.
Keywords: frail patients; older patients; age; stroke ... See more keywords
Catheter ablation can improve survival with the reduction of heart failure in frail patients with atrial fibrillation
Sign Up to like & getrecommendations! Published in 2020 at "European Heart Journal"
DOI: 10.1093/ehjci/ehaa946.0557
Abstract: It is unclear whether catheter ablation is beneficial in frail patients with AF. This study aimed to evaluate whether catheter ablation reduces death and other outcomes in real-world frail patients with atrial fibrillation (AF). Out… read more here.
Keywords: frail patients; ablation; heart failure; catheter ablation ... See more keywords