PredCID: prediction of driver frameshift indels in human cancer
Sign Up to like & getrecommendations! Published in 2021 at "Briefings in bioinformatics"
DOI: 10.1093/bib/bbaa119
Abstract: The discrimination of driver from passenger mutations has been a hot topic in the field of cancer biology. Although recent advances have improved the identification of driver mutations in cancer genomic research, there is no… read more here.
Keywords: frameshift; frameshift indels; driver frameshift; cancer ... See more keywords
Frameshift indels introduced by genome editing can lead to in-frame exon skipping
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DOI: 10.1371/journal.pone.0178700
Abstract: The introduction of frameshift indels by genome editing has emerged as a powerful technique to study the functions of uncharacterized genes in cell lines and model organisms. Such mutations should lead to mRNA degradation owing… read more here.
Keywords: genome editing; indels introduced; frameshift indels; exon skipping ... See more keywords