A scalable framework for the discovery of functional helicase substrates and helicase-driven regulatory switches
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2209608119
Abstract: Significance Helicases are ubiquitous NTP-dependent enzymes that disrupt nucleic acid (NA) helices and NA–protein interactions. Despite the implication of helicases in many cellular processes and diseases, their target repertoires and determinants of functional specialization often… read more here.
Keywords: framework discovery; helicase substrates; scalable framework; functional helicase ... See more keywords
A machine learning framework for discovery and enrichment of metagenomics metadata from open access publications
Sign Up to like & getrecommendations! Published in 2022 at "GigaScience"
DOI: 10.1093/gigascience/giac077
Abstract: Abstract Metagenomics is a culture-independent method for studying the microbes inhabiting a particular environment. Comparing the composition of samples (functionally/taxonomically), either from a longitudinal study or cross-sectional studies, can provide clues into how the microbiota… read more here.
Keywords: framework discovery; metagenomics studies; machine learning; europe pmc ... See more keywords