Articles with "framework quantifying" as a keyword



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Population PBPK modelling of trastuzumab: a framework for quantifying and predicting inter-individual variability

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Published in 2017 at "Journal of Pharmacokinetics and Pharmacodynamics"

DOI: 10.1007/s10928-017-9515-3

Abstract: In this work we proposed a population physiologically-based pharmacokinetic (popPBPK) framework for quantifying and predicting inter-individual pharmacokinetic variability using the anti-HER2 monoclonal antibody (mAb) trastuzumab as an example. First, a PBPK model was developed to… read more here.

Keywords: variability; inter individual; quantifying predicting; framework quantifying ... See more keywords
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A unifying framework for quantifying and comparing n‐dimensional hypervolumes

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Published in 2021 at "Methods in Ecology and Evolution"

DOI: 10.1111/2041-210x.13665

Abstract: The quantification of Hutchinson's n‐dimensional hypervolume has enabled substantial progress in community ecology, species niche analysis and beyond. However, most existing methods do not support a partitioning of the different components of hypervolume. Such a… read more here.

Keywords: distance; ecology; niche; unifying framework ... See more keywords
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An ensemble covariance framework for quantifying forced climate variability and its time of emergence

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Published in 2018 at "Journal of Climate"

DOI: 10.1175/jcli-d-17-0719.1

Abstract: AbstractClimate variability and its response to increasing greenhouse gases are important considerations for impacts and adaptation. Modeling studies commonly assess projected changes in variabilit... read more here.

Keywords: covariance framework; climate; quantifying forced; variability ... See more keywords