Difficulties translating antisense-mediated activation of Frataxin expression from cell culture to mice
Sign Up to like & getrecommendations! Published in 2022 at "RNA Biology"
DOI: 10.1080/15476286.2022.2043650
Abstract: ABSTRACT Friedreich’s ataxia (FA) is an inherited neurodegenerative disorder caused by decreased expression of frataxin (FXN) protein. Previous studies have shown that antisense oligonucleotides (ASOs) and single-stranded silencing RNAs can be used to increase expression… read more here.
Keywords: frataxin expression; expression; expression cell; frataxin ... See more keywords