Quantitative single molecule analysis of podoplanin clustering in fibroblastic reticular cells uncovers CD44 function
Sign Up to like & getrecommendations! Published in 2023 at "Open Biology"
DOI: 10.1098/rsob.220377
Abstract: Upon initial immune challenge, dendritic cells (DCs) migrate to lymph nodes and interact with fibroblastic reticular cells (FRCs) via C-type lectin-like receptor 2 (CLEC-2). CLEC-2 binds to the membrane glycoprotein podoplanin (PDPN) on FRCs, inhibiting… read more here.
Keywords: single molecule; reticular cells; fibroblastic reticular; quantitative single ... See more keywords