Ionic Liquid Forms of Weakly Acidic Drugs in Oral Lipid Formulations: Preparation, Characterization, in Vitro Digestion, and in Vivo Absorption Studies.
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DOI: 10.1021/acs.molpharmaceut.7b00442
Abstract: This study aimed to transform weakly acidic poorly water-soluble drugs (PWSD) into ionic liquids (ILs) to promote solubility in, and the utility of, lipid-based formulations. Ionic liquids (ILs) were formed directly from tolfenamic acid (Tolf),… read more here.
Keywords: absorption; tolf; weakly acidic; drug ... See more keywords
PHARMACOKINETICS OF CEFTIOFUR CRYSTALLINE FREE ACID STERILE SUSPENSION IN GREEN IGUANAS (IGUANA IGUANA) AFTER SINGLE INTRAMUSCULAR ADMINISTRATION
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Zoo and Wildlife Medicine"
DOI: 10.1638/2017-0163r.1
Abstract: Abstract The objective of this study was to establish the pharmacokinetic parameters of ceftiofur crystalline free acid (CCFA) for a single intramuscular injection in green iguanas (Iguana iguana). Six green iguanas received an injection of… read more here.
Keywords: ceftiofur crystalline; crystalline free; iguana; green iguanas ... See more keywords
PHARMACOKINETICS OF CEFTIOFUR CRYSTALLINE-FREE ACID ADMINISTERED VIA INTRAMUSCULAR INJECTION IN WHOOPING CRANES (GRUS AMERICANA)
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DOI: 10.1638/2022-0058
Abstract: Abstract: The objective of this study was to evaluate the pharmacokinetic properties of a single dose of ceftiofur crystalline-free acid (CCFA) in whooping cranes (Grus americana). Ceftiofur crystalline-free acid is a long-acting, injectable, third-generation cephalosporin… read more here.
Keywords: ceftiofur crystalline; crystalline free; free acid; whooping cranes ... See more keywords
Pharmacokinetics of a Single Intramuscular Injection of Ceftiofur Crystalline Free Acid in Bald Eagles (Haliaeetus leucocephalus)
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DOI: 10.1647/20-00038
Abstract: Abstract: The objective of this study was to evaluate the pharmacokinetic properties of ceftiofur crystalline free acid (CCFA) administered intramuscularly at dosages of 10 and 20 mg/kg in bald eagles (BAEAs) (Haliaeetus leucocephalus). Ceftiofur crystalline… read more here.
Keywords: ceftiofur crystalline; crystalline free; bald eagles; haliaeetus leucocephalus ... See more keywords
Thermal and Structural Characterization of Two Crystalline Polymorphs of Tafamidis Free Acid
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DOI: 10.3390/molecules27217411
Abstract: Tafamidis, chemical formula C14H7Cl2NO3, is a drug used to delay disease progression in adults suffering from transthyretin amyloidosis, and is marketed worldwide under different tradenames as a free acid or in the form of its… read more here.
Keywords: thermal structural; polymorphs; crystalline; acid ... See more keywords