Solvent-Free N-Alkylation and Dehydrogenative Coupling Catalyzed by a Highly Active Pincer-Nickel Complex
Sign Up to like & getrecommendations! Published in 2020 at "Organometallics"
DOI: 10.1021/acs.organomet.0c00233
Abstract: The synthesis and characterization of a pincer-nickel complex of the type (iPr2NNN)NiCl2(CH3CN) is reported here. We have demonstrated the utility of this pincer-nickel complex (0.02 and 0.002 mol ... read more here.
Keywords: free alkylation; nickel complex; solvent free; pincer nickel ... See more keywords
Metal and Activating Group Free C-4 Alkylation of Isoquinolines via a Temporary Dearomatization Strategy
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DOI: 10.1021/acs.orglett.2c04149
Abstract: A simple method for the C-4 alkylation of isoquinolines is described using benzoic acid as a nucleophilic reagent and vinyl ketones as an electrophile. The reaction shows tolerance for substitution at C-3, and C-5–C-8 positions… read more here.
Keywords: activating group; group free; alkylation; metal activating ... See more keywords