Disentangling The Shared Genetic Etiology Between Serum Cholesterol And Suicide Risk: A Potential Moderating Role For Cholesterol Efflux
Sign Up to like & getrecommendations! Published in 2017 at "European Neuropsychopharmacology"
DOI: 10.1016/j.euroneuro.2016.09.588
Abstract: Background The link between serum cholesterol and suicide attempts is well established, several studies suggest that lower levels of cholesterol are associated with increased risk of mortality from suicide. However, the etiology of this association… read more here.
Keywords: etiology; cholesterol; cholesterol efflux; free cholesterol ... See more keywords
Molecular mechanisms for ABCA1-mediated cholesterol efflux.
Sign Up to like & getrecommendations! Published in 2022 at "Cell cycle"
DOI: 10.1080/15384101.2022.2042777
Abstract: The maintenance of cellular cholesterol homeostasis is essential for normal cell function and viability. Excessive cholesterol accumulation is detrimental to cells and serves as the molecular basis of many diseases, such as atherosclerosis, Alzheimer's disease,… read more here.
Keywords: mediated cholesterol; abca1 mediated; cholesterol; cholesterol efflux ... See more keywords
Visible-free cholesterol crystal emboli adjacent to microinfarcts in myocardial capillaries and arterioles on H&E-stained frozen sections of an autopsied patient
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DOI: 10.1136/bcr-2018-225558
Abstract: The number of released free cholesterol crystal emboli (fCCE) and their role during percutaneous coronary intervention (PCI) in acute coronary syndrome (ACS) have not been documented yet. Furthermore, fCCE manifesting in the coronary lumen following… read more here.
Keywords: microscopy; cholesterol crystal; crystal emboli; free cholesterol ... See more keywords
IDDF2019-ABS-0081 Portal free cholesterol and oxidized-LDL accumulation is associated with plaque formation and inflammation in human NAFLD
Sign Up to like & getrecommendations! Published in 2019 at "Gut"
DOI: 10.1136/gutjnl-2019-iddfabstracts.88
Abstract: Background Macrophage uptake of oxidized low-density lipoprotein (oxLDL) which may result in the accumulation of free cholesterol and subsequent crystal formation that can induce NLRP3 inflammasome activation. Hepatic free cholesterol content is significantly increased in… read more here.
Keywords: free cholesterol; cholesterol; accumulation; plaque formation ... See more keywords
Diagnostic Value of Systemic Cholesteryl Ester/Free Cholesterol Ratio in Hepatocellular Carcinoma.
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DOI: 10.21873/anticanres.11721
Abstract: BACKGROUND Hepatocellular carcinoma (HCC) most commonly occurs in the setting of liver cirrhosis which is characterized by low serum lipids. We hypothesized that composition of lipoproteins and consequently lipid species ratios are mostly unchanged in… read more here.
Keywords: hepatocellular carcinoma; free cholesterol; cholesteryl ester; ester free ... See more keywords
Altered Distribution of Unesterified Cholesterol among Lipoprotein Subfractions of Patients with Diabetes Mellitus Type 2
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DOI: 10.3390/biom13030497
Abstract: Biomarkers are important tools to improve the early detection of patients at high risk for developing diabetes as well as the stratification of diabetic patients towards risks of complications. In addition to clinical variables, we… read more here.
Keywords: small hdl; free cholesterol; cholesterol; hdl ... See more keywords
Free Cholesterol Accelerates Aβ Self-Assembly on Membranes at Physiological Concentration
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DOI: 10.3390/ijms23052803
Abstract: The effects of membranes on the early-stage aggregation of amyloid β (Aβ) have come to light as potential mechanisms by which neurotoxic species are formed in Alzheimer’s disease. We have shown that direct Aβ-membrane interactions… read more here.
Keywords: cholesterol accelerates; accelerates self; cholesterol; aggregation ... See more keywords