Stakeholder Perspectives on Minimum Clinically Important Difference and Noninferiority Margin for Hospital-Free Days to Assess Interventions.
Sign Up to like & getrecommendations! Published in 2023 at "JAMA internal medicine"
DOI: 10.1001/jamainternmed.2023.0918
Abstract: This survey study examined perceptions of patients, caregivers and health care professionals on the number of hospital-free days required for detection of a minimum clinically important difference or noninferiority margin of new interventions. read more here.
Keywords: important difference; difference noninferiority; free days; clinically important ... See more keywords
Leveraging smart technologies to improve the management of diabetic foot ulcers and extend ulcer‐free days in remission
Sign Up to like & getrecommendations! Published in 2020 at "Diabetes/Metabolism Research and Reviews"
DOI: 10.1002/dmrr.3239
Abstract: The prevalent and long neglected diabetic foot ulcer (DFU) and its related complications rank among the most debilitating and costly sequelae of diabetes. Management of the DFU is multifaceted and requires constant monitoring from patients,… read more here.
Keywords: ulcer free; remission; free days; management ... See more keywords
Patient and Caregiver Health State Utilities in Lennox-Gastaut Syndrome and Dravet Syndrome.
Sign Up to like & getrecommendations! Published in 2021 at "Clinical therapeutics"
DOI: 10.1016/j.clinthera.2021.09.017
Abstract: PURPOSE Lennox-Gastaut syndrome (LGS) and Dravet syndrome (DS) are rare, treatment-resistant forms of epilepsy characterized by childhood onset of seizures. Cost-effectiveness analysis for new antiseizure medications typically requires health state utilities (HSUs) that reflect the… read more here.
Keywords: caregiver; patient caregiver; free days; seizure free ... See more keywords
Complementing the Social Jet Lag by considering pristine internal time
Sign Up to like & getrecommendations! Published in 2017 at "Chronobiology International"
DOI: 10.1080/07420528.2017.1356328
Abstract: In 2003, Roenneberg and colleagues defined the Social Jet Lag (SJL) as the difference between the mid sleep times on free days and on work days (Roenneberg et al., 2003). In the recent article, Jankowski… read more here.
Keywords: time; free days; work days; day ... See more keywords
The Association Between Inhaled Nitric Oxide Treatment and ICU Mortality and 28-Day Ventilator-Free Days in Pediatric Acute Respiratory Distress Syndrome*
Sign Up to like & getrecommendations! Published in 2018 at "Critical Care Medicine"
DOI: 10.1097/ccm.0000000000003312
Abstract: Objectives: To investigate the association between inhaled nitric oxide treatment and ICU mortality and 28-day ventilator-free days in pediatric acute respiratory distress syndrome. Design: Retrospective cohort study. A propensity score for inhaled nitric oxide treatment… read more here.
Keywords: free days; ventilator free; inhaled nitric; nitric oxide ... See more keywords
Early Clinical and Electrophysiological Brain Dysfunction Is Associated With ICU Outcomes in COVID-19 Critically Ill Patients With Acute Respiratory Distress Syndrome: A Prospective Bicentric Observational Study.
Sign Up to like & getrecommendations! Published in 2022 at "Critical care medicine"
DOI: 10.1097/ccm.0000000000005491
Abstract: OBJECTIVES Describe the prevalence of acute cerebral dysfunction and assess the prognostic value of an early clinical and electroencephalography (EEG) assessment in ICU COVID-19 patients. DESIGN Prospective observational study. SETTING Two tertiary critical care units… read more here.
Keywords: ill patients; critically ill; dysfunction; early clinical ... See more keywords
Reporting of Hospital-Free Days As an Outcome Measure in Critical Care Trials: A Systematic Review
Sign Up to like & getrecommendations! Published in 2025 at "Critical Care Medicine"
DOI: 10.1097/ccm.0000000000006858
Abstract: Objectives: To synthesize the existing use, definitions, and variation in the application of hospital-free days (HFDs) as an outcome measure in randomized controlled trials (RCTs) of critically ill adults. Data Sources: Trial registries (ISRCTN, ClinicalTrials.gov)… read more here.
Keywords: hospital free; outcome measure; free days; hfd ... See more keywords
Clinical significance of urinary obstruction in critically ill patients with urinary tract infections
Sign Up to like & getrecommendations! Published in 2020 at "Medicine"
DOI: 10.1097/md.0000000000018519
Abstract: Abstract Urinary obstruction may be a complicating factor in critically ill patients with urinary tract infections (UTIs) and requires efforts for identifying and controlling the infection source. However, its significance in clinical practice is uncertain.… read more here.
Keywords: ill patients; patients urinary; critically ill; free days ... See more keywords
Comparing Hospital-Free Days by Frailty Status Among Those Undergoing Surgical Intervention for Cardiovascular Disease.
Sign Up to like & getrecommendations! Published in 2025 at "Journal of the American College of Surgeons"
DOI: 10.1097/xcs.0000000000001408
Abstract: BACKGROUND Aging patients face increasing comorbid conditions, most commonly atherosclerotic cardiovascular diseases (ASCVD), often treated surgically; however, with aging also comes frailty portending adverse postoperative outcomes. Assessing outcomes in a frail surgical cohort necessitates the… read more here.
Keywords: hospital free; mortality; free days; status ... See more keywords
Seizure-free days as a novel outcome in patients with Lennox-Gastaut syndrome: post hoc analysis of patients receiving cannabidiol in two randomized controlled trials.
Sign Up to like & getrecommendations! Published in 2023 at "Epilepsia"
DOI: 10.1111/epi.17618
Abstract: OBJECTIVE In this post hoc analysis, we aimed to assess seizure-free days as a potential new outcome measure to use in randomized placebo-controlled trials (RCTs) of patients with Lennox-Gastaut syndrome (LGS). METHODS In two phase… read more here.
Keywords: hoc analysis; seizure free; free days; post hoc ... See more keywords
Analysis of the symptom response to esomeprazole 20 mg over days 1–4 of a 14-day course of treatment for frequent heartburn: results of two randomised controlled trials
Sign Up to like & getrecommendations! Published in 2019 at "BMJ Open Gastroenterology"
DOI: 10.1136/bmjgast-2019-000278
Abstract: Background Drug exposure and corresponding antisecretory effects increase over the first 4–5 days of esomeprazole treatment. To date, this effect has not been correlated with symptomatic improvement. Therefore, the efficacy of esomeprazole was evaluated on… read more here.
Keywords: heartburn; treatment; free days; heartburn free ... See more keywords