Catalyst and additive free 6-endo-dig cyclization of ortho-alkynylarylaldimines in water: An environmentally friendly access to isoquinolines
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DOI: 10.1016/j.tetlet.2019.151454
Abstract: Abstract A novel and sustainable route for the synthesis of isoquinoline was developed by reacting 2-ethynylbenzaldehyde with ammonium hydroxide in water. This method provides a convenient, atom-economical, and catalyst-free access to diversely substituted isoquinolines with… read more here.
Keywords: additive free; catalyst additive; water; free endo ... See more keywords