Injectable Dendrimer Hydrogel Delivers Melphalan in Both Conjugated and Free Forms for Retinoblastoma.
Sign Up to like & getrecommendations! Published in 2024 at "Biomacromolecules"
DOI: 10.1021/acs.biomac.4c00597
Abstract: We report the successful synthesis of an injectable dendrimer hydrogel (DH) carrying melphalan, a clinical drug for retinoblastoma treatment, in both conjugated and free forms. Polyamidoamine (PAMAM) dendrimer generation 5 (G5) is surface-modified with an… read more here.
Keywords: melphalan; dendrimer hydrogel; conjugated free; free forms ... See more keywords
Peptidoglycan-tethered and free forms of the Braun lipoprotein are in dynamic equilibrium in Escherichia coli
Sign Up to like & getrecommendations! Published in 2024 at "eLife"
DOI: 10.1101/2023.09.26.559517
Abstract: Peptidoglycan (PG) is a giant macromolecule that completely surrounds bacterial cells and prevents lysis in hypo-osmotic environments. This net-like macromolecule is made of glycan strands linked to each other by two types of transpeptidases that… read more here.
Keywords: braun lipoprotein; dynamic equilibrium; peptidoglycan tethered; free forms ... See more keywords