Articles with "free heme" as a keyword



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The Antagonizing Role of Heme in the Antimalarial Function of Artemisinin: Elevating Intracellular Free Heme Negatively Impacts Artemisinin Activity in Plasmodium falciparum

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Published in 2022 at "Molecules"

DOI: 10.3390/molecules27061755

Abstract: The rich source of heme within malarial parasites has been considered to underly the action specificity of artemisinin. We reasoned that increasing intraparasitic free heme levels might further sensitize the parasites to artemisinin. Various means,… read more here.

Keywords: negatively impacts; heme levels; heme; free heme ... See more keywords