Carrier-Free Immunotherapeutic Nano-Booster with Dual Synergistic Effects Based on Glutaminase Inhibition Combined with Photodynamic Therapy.
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DOI: 10.1021/acsnano.2c11037
Abstract: The immunotherapeutic effect elicited by photodynamic therapy (PDT) is attenuated by tumor defense mechanisms associated with glutamine metabolism, including the metabolic regulation of redox homeostasis and the limitation of the immunosuppressive tumor microenvironment (ITM). Herein,… read more here.
Keywords: free immunotherapeutic; synergistic effects; carrier free; dual synergistic ... See more keywords