Calibration-free NGS quantitation of mutations below 0.01% VAF.
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DOI: 10.1038/s41467-021-26308-6
Abstract: Quantitation of rare somatic mutations is essential for basic research and translational clinical applications including minimal residual disease (MRD) detection. Though unique molecular identifier (UMI) has suppressed errors for rare mutation detection, the sequencing depth… read more here.
Keywords: quantitation mutations; quantitation; calibration free; free ngs ... See more keywords