Treatment of Adults With Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia-From Intensive Chemotherapy Combinations to Chemotherapy-Free Regimens: A Review.
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DOI: 10.1001/jamaoncol.2022.2398
Abstract: Importance With the advent of potent BCR::ABL1 tyrosine kinase inhibitors (TKIs), Philadelphia chromosome-positive (Ph-positive) acute lymphoblastic leukemia (ALL) is now a relatively favorable-risk acute leukemia. In this review, we discuss the current evidence for frontline… read more here.
Keywords: acute; allogeneic sct; free regimens; chemotherapy free ... See more keywords
Role of ribavirin in the treatment of hepatitis C virus-associated mixed cryoglobulinemia with interferon-free regimens
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DOI: 10.1007/s00705-017-3684-7
Abstract: Mixed cryoglobulinemia (MC) is the most common extrahepatic manifestation of chronic hepatitis C (CHC), with the presence of symptoms in 10–15% of cases. There have been encouraging data regarding immunological and clinical responses in patients… read more here.
Keywords: free regimens; role ribavirin; response; treatment ... See more keywords
Hepatitis C treatment from “response‐guided” to “resource‐guided” therapy in the transition era from interferon‐containing to interferon‐free regimens
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DOI: 10.1111/jgh.13747
Abstract: Peginterferon/ribavirin has been the standard‐of‐care for chronic hepatitis C virus (HCV) infections: 48 weeks for genotype 1 or 4 (HCV‐1/4) and 24 weeks for HCV‐2/3. Response‐guided therapy recommended shorter 24‐ and 16‐week regimens for HCV‐1… read more here.
Keywords: free regimens; interferon free; interferon containing; response ... See more keywords
The effect of interferon‐free regimens on health‐related quality of life in East Asian patients with chronic hepatitis C
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DOI: 10.1111/liv.13650
Abstract: Interferon (IFN)‐based regimens cause significant impairment of health‐related quality of life (HRQL). Hepatitis C virus (HCV) cure with IFN‐free regimens improves HRQL. The effect of these regimens on HRQL in East Asian HCV patients is… read more here.
Keywords: free regimens; interferon; health related; related quality ... See more keywords
Abstract P3-11-13: Efficacy and Safety of Chemo-Free Regimens in HER2-Positive Early Breast Cancer: A Comprehensive Systematic Review and Meta-Analysis
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DOI: 10.1158/1557-3265.sabcs24-p3-11-13
Abstract: Background: Human epidermal growth factor receptor-2 (HER2)-positive breast cancer is a rapidly growing cancer that has poor outcomes if left untreated. Generally, this cancer requires treatment with aggressive chemotherapy and HER2-targeting therapies. However, there is… read more here.
Keywords: cancer; breast cancer; free regimens; her2 positive ... See more keywords