Metal-free regioselective construction of diazabenzo[ e ]acephenanthrylene-1,2-dicarboxylates via a phosphine-mediated cycloadditon
Sign Up to like & getrecommendations! Published in 2017 at "Tetrahedron"
DOI: 10.1016/j.tet.2017.06.010
Abstract: Abstract A number of new diazabenzo[e]acephenanthrylene-1,2-dicarboxylate derivatives have been prepared regiospecifically in moderate to good yields from the triphenylphosphine-mediated cyclocondensation reaction of dialkyl acetylenedicarboxylates with 1-(4-aryl)-2-(11H-indeno[1,2-b]quinoxalin-11-ylidene)ethanones, derived from reaction of ninhydrin, o-phenylenediamine, and 1-aryl-2-(triphenylphosphoranylidene)ethanones. read more here.
Keywords: acephenanthrylene; regioselective construction; construction diazabenzo; metal free ... See more keywords
Transition metal-free regioselective synthesis of triazolyl aliphatic sulfonyl fluorides
Sign Up to like & getrecommendations! Published in 2021 at "Tetrahedron"
DOI: 10.1016/j.tet.2021.132425
Abstract: Abstract An efficient and metal-free method for exclusively regioselective construction of aliphatic sulfonyl fluoride moiety at the C4 position of 1,2,3-triazole ring was successfully developed from the cycloaddition between but-3-ene-1, 3-disulfonyl difluoride (BDF) and organic… read more here.
Keywords: metal free; transition metal; aliphatic sulfonyl; free regioselective ... See more keywords
Transition-Metal-Free Regioselective Intermolecular Hydroamination of Conjugated 1,3-Dienes with Heterocyclic Amines.
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DOI: 10.1021/acs.orglett.2c00810
Abstract: The unique property of hexafluoroisopropanol (HFIP) enables the regioselective hydroamination of 1,3-dienes with nitrogen heterocycles in a Markovnikov manner in the presence of catalytic Brønsted acid. This transition-metal-free intermolecular hydroamination protocol is achieved under mild… read more here.
Keywords: heterocyclic amines; metal free; transition metal; hydroamination ... See more keywords
Metal-free regioselective C5-cyanoalkylation of the 8-aminoquinolineamides/sulfonamides via oxidative cross-dehydrogenative coupling with alkylnitriles
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DOI: 10.1039/d1qo00570g
Abstract: A practical, versatile and Metal-free regioselective C5-cyanoalkylation of the 8-aminoquinolineamides/sulfonamides with acetonitrile has been described. read more here.
Keywords: aminoquinolineamides sulfonamides; cyanoalkylation aminoquinolineamides; regioselective cyanoalkylation; free regioselective ... See more keywords
Transition-metal-free regioselective hydroamination of styrenes with amino-heteroarenes.
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DOI: 10.1039/d2cc02781j
Abstract: The base-mediated anti-Markovnikov hydroamination of functionally varied styrenes with amino-substituted pyridine, quinoline, pyrimidine, pyrazine, and phenanthridine with excellent regioselectivity has been described. Double hydroamination was observed chemoselectively on the secondary amine, leaving the primary amine… read more here.
Keywords: regioselective hydroamination; metal free; transition metal; hydroamination ... See more keywords
Metal-free regioselective mono- and poly-halogenation of 2-substituted indazoles
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DOI: 10.1039/d2ra07398f
Abstract: An unprecedented metal-free regioselective halogenation of 2H-indazoles has been revealed, which not only realized the highly selective synthesis of mono-halogenated products, but also completed poly-halogenations by fine tuning the reaction conditions. Various mono-/poly-/hetero-halogenated indazoles were… read more here.
Keywords: free regioselective; metal free; halogenation; mono poly ... See more keywords