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Transition-metal-free site-selective C–F bond activation for synthesis of 8-aminoquinolines

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Published in 2017 at "Tetrahedron Letters"

DOI: 10.1016/j.tetlet.2017.09.069

Abstract: Abstract An efficient and general selective method for the synthesis of 8-aminoquinoline derivatives has been disclosed through transition metal direct C–N coupling from fluoroquinolines and arylamines. Significantly, good chemo- and regio-selectivity was observed for polyfluoroquinolines… read more here.

Keywords: transition metal; site selective; bond; free site ... See more keywords