Simvastatin nanoliposome induces myocardial and hepatic toxicities due to its absorption enhancement in mice
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DOI: 10.1016/j.ajps.2019.02.002
Abstract: Nanoliposome is a useful dosage form to increase solubility and absorption of simvastatin (SMV), and consequently improves its therapeutic effects. However, in vivo toxicity of SMV could also be elevated accompanied by the absorption enhancement,… read more here.
Keywords: smv lipo; absorption enhancement; smv; free smv ... See more keywords