Bacterial lipopolysaccharide (LPS) inhibits colonic uptake of the microbiota-generated forms of vitamin B1 [thiamin pyrophosphate (TPP), and free thiamin] via different mechanisms
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DOI: 10.1152/physiol.2023.38.s1.5731488
Abstract: LPS is a major component of the outer membrane of Gram-negative bacteria. The gut is exposed to high levels of this endotoxin in conditions such as IBD, necrotizing enterocolitis, and sepsis. LPS affects different aspects… read more here.
Keywords: inhibition; free thiamin; physiology; colonic uptake ... See more keywords