Pharmacokinetics of freebase nicotine and nicotine salts following subcutaneous administration in male rats.
Sign Up to like & getrecommendations! Published in 2022 at "Drug testing and analysis"
DOI: 10.1002/dta.3363
Abstract: Nicotine lactate, nicotine tartrate, nicotine benzoate, and freebase nicotine (FBN) are four forms of nicotine salt systems that are present in tobacco products. However, few in vivo studies have compared their pharmacological (pK) efficacies, which… read more here.
Keywords: nicotine salts; nicotine nicotine; nicotine; freebase nicotine ... See more keywords
Examining the role of freebase nicotine in the harm reduction potential of oral nicotine pouches versus moist snuff: A randomized crossover trial.
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DOI: 10.1111/add.70114
Abstract: BACKGROUND AND AIMS Oral nicotine pouches (ONPs) contain varying proportions of freebase nicotine (FBN), with higher FBN expected to increase nicotine delivery across the oral mucosa. Because ONPs contain fewer toxicants than moist snuff and… read more here.
Keywords: oral nicotine; freebase nicotine; nicotine pouches; snuff ... See more keywords
Total and unprotonated (freebase) nicotine content in new types of oral ‘tobacco-free’ nicotine products
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DOI: 10.1136/tc-2024-058914
Abstract: Significance Nicotine-containing products, labelled as being ‘tobacco-free’ nicotine (TFN), are marketed to consumers as alternatives to conventional tobacco products. Little is known about these emerging products and their contents. Methods Moisture, total nicotine and pH… read more here.
Keywords: nicotine content; freebase nicotine; tobacco free; nicotine ... See more keywords