Germline MC1R variants and frequency of somatic BRAF, NRAS, and TERT mutations in melanoma: Literature review and meta‐analysis
Sign Up to like & getrecommendations! Published in 2021 at "Molecular Carcinogenesis"
DOI: 10.1002/mc.23280
Abstract: Germline variants of the melanocortin‐1‐receptor (MC1R) gene are the most common genetic trait predisposing to cutaneous melanoma (CM). Here, we performed a literature review and meta‐analysis of the association between MC1R gene variants and the… read more here.
Keywords: mc1r gene; review meta; frequency somatic; braf nras ... See more keywords
Limited accumulation of high-frequency somatic mutations in a 1,700-year-old Osmanthus fragrans tree.
Sign Up to like & getrecommendations! Published in 2022 at "Tree physiology"
DOI: 10.1093/treephys/tpac058
Abstract: Lifespan varies greatly between and within species. Mutation accumulation is considered an important factor explaining this life history trait. However, direct assessment of somatic mutations in long-lived species is still rare. In this study, we… read more here.
Keywords: high frequency; accumulation; frequency somatic; mutation ... See more keywords